Non-melanoma skin cancers, including squamous cell carcinoma (SCC), represent the most common form of cancer in Caucasians, with a continuing increase in incidence worldwide.
The role of ultraviolet radiation (UV) in the genesis of SCC is crucial; as UV radiation can damage DNA directly or through reactive oxygen species. While exposure to UV radiation has been a well-established risk factor for these skin conditions, recent studies have sparked interest in the potential role of HPV in their pathogenesis.
In a study partially supported by the iToBoS project, the group from UNITS investigated the prevalence of specific HPV genotypes in patients diagnosed with Bowen's disease and in situ SCC, comparing the results with some controls.
The data collected from this study are published in the Journal of Clinical Medicine at the following link https://www.mdpi.com/2077-0383/13/4/1091 .