Intelligent Total Body Scanner (iToBoS) System is a larger international project for developing an artificial intelligence (AI) assisted diagnostic platform for the early detection of melanoma.
This platform will include a total body scanner, powered with high-resolution cameras, and a Computer Aided Diagnostics (CAD) tool to integrate data sources such medical records, genomics data and imaging data. In a first part of the project images of Total Body Photography using polarised light will be produced from patients using a commercial medical device called VECTRA 360 (Canfield corp. US). This clinical part of the study intent to collect participants data from two international centres: Hospital Clinic de Barcelona and Queensland University. In QA the study will be retrospective including images and data of 150 patients. In HCB the study will prospectively contribute with 150 participants.
At this phase, the images are taken using the body scanner VECTRA WB360 imaging from patients attending their dermatologic examinations at the Dermatology Department of the Hospital Clinic of Barcelona. This medical device is used to capture images of the entire skin surface in macro high quality resolution using 96 cameras. All the images are stitch together creating a 3D personal anonymous avatar. Moreover, the imaging analysis will include the skin phototype, the number of nevi count, the size and location of nevi.
During the skin examination, dermoscopy images will be taken of any concerning lesions and lesions over 5mm in diameter, which will be mapped to the total body images taken with the VECTRA system. Additionally, some dermoscopy images per participant will be taken of benign lesions from various body sites (trunk, arms, and legs), for the purpose of training the CAD system to detect skin lesions categorize risk of lesions and map lesions to a generic avatar. These will include a diverse range of malignant and benign lesions including, but not limited to, intraepithelial carcinoma; basal cell carcinoma; solar lentigo, seborrheic keratosis and lichen planus-like keratosis; dermatofibroma; melanoma; melanocytic naevus; and vascular lesions.
The aim of this first prospective clinical study is to train the CAD to integrate the clinical, genetics and imaging data, while the iToBoS System is being manufactured.
G.Rezze, J.Malvehy. Hospital Clinic of Barcelona, IDIBAPS. iTOBOS